Gerber Lab at ICML Workshop on Computational Biology 2023

Gerber Lab at ICML Workshop on Computational Biology 2023

The ICML Workshop on Computational Biology (WCB) highlights how ML approaches can be tailored to making both translational and basic scientific discoveries with biological data, such as genetic sequences, cellular features or protein structures and imaging datasets, among others. It aims to bring together interdisciplinary ML researchers working in areas such as computational genomics; neuroscience; metabolomics; proteomics; bioinformatics; cheminformatics; pathology; radiology; evolutionary biology; population genomics; phenomics; ecology, cancer biology; causality; representation learning and disentanglement to present recent advances and open questions to the machine learning community.

The Gerber Lab had the following two papers accepted:

Gerber GK, Bhattarai SK, Du M, Glickman MS, Bucci V. Discovery of Host-Microbiome Interactions Using Multi-Modal, Sparse, Time-Aware, Bayesian Network-Structured Neural Topic Models. International Conference on Machine Learning Workshop on Computational Biology, 2023.

Uppal G, Urtecho G, Richardson M, Moody T, Wang HH, Gerber GK. MC-SPACE: Microbial communities from spatially associated counts engine. International Conference on Machine Learning Workshop on Computational Biology, 2023.

 

Algorithmic fairness in artificial intelligence for medicine and healthcare: Nature Biomedical Engineering

Algorithmic fairness in artificial intelligence for medicine and healthcare: Nature Biomedical Engineering

In healthcare, the development and deployment of insufficiently fair systems of artificial intelligence (AI) can undermine the delivery of equitable care. Assessments of AI models stratified across subpopulations have revealed inequalities in how patients are diagnosed, treated and billed. In this Perspective, we outline fairness in machine learning through the lens of healthcare, and discuss how algorithmic biases (in data acquisition, genetic variation and intra-observer labelling variability, in particular) arise in clinical workflows and the resulting healthcare disparities. We also review emerging technology for mitigating biases via disentanglement, federated learning and model explainability, and their role in the development of AI-based software as a medical device.

Chen RJ, Wang JJ, Williamson DFK, Chen TY, Lipkova J, Lu MY, Sahai S, Mahmood F. Algorithmic fairness in artificial intelligence for medicine and healthcare. Nat Biomed Eng. 2023 06; 7(6):719-742. PMID: 37380750.