Building for Transformative Medicine, 60 Fenwood Road, Boston MA

Ami S. Bhatt MD PhD, Stanford – “From precision microbiome genomics to precision medicine”

Hybrid - Wolf Conference Center and Zoom 3rd Floor, 60 Fenwood Road, Boston, MA, Massachusetts

More than 1,000 species of bacteria, archaea, viruses and fungi live in the human gut. Far from being passive passengers, these organisms strongly interact with one another and with their host's metabolism and immune system. Compelling early experiments have demonstrated associations between the intestinal microbiome composition and obesity, cardiovascular diseases, and certain cancer chemotherapies' efficacy. […]

Uthsav Chitra, Princeton – “Modeling spatial variation in gene expression and copy number aberrations”

Hybrid - Wolf Conference Center and Zoom 3rd Floor, 60 Fenwood Road, Boston, MA, Massachusetts

Spatially resolved transcriptomics (SRT) technologies measure gene expression at thousands of spatial locations in a tissue slice, enabling the identification of spatially varying genes and cell populations. In this talk, I will present two computational approaches for modeling spatial variation in SRT data. First, I will describe Belayer, an algorithm that models both discrete and […]