Division of Computational Pathology

Advanced computation applied to understanding, diagnosis and treatment of human disease

The Division in the BWH Department of Pathology focuses on research in areas of excellence leveraging unique strengths of the Department, including pathology imaging and the microbiome, with plans to add other foci soon.


Division News

December 2021: Gerber Lab Preprint

Dawkins JJ, Jessica RA, Gibson TE, McClure E, Delaney M, Bry L, Maringanti VS, Bucci V, Gerber GK. MDITRE: scalable and interpretable machine learning for predicting host status from temporal microbiome dynamics. bioRxiv 2021.12.15.472835; doi: https://doi.org/10.1101/2021.12.15.472835

December 2021: Gerber and Gibson Lab Preprint

Gibson TE, Kim Y, Acharya S, Kaplan DE, DiBenedetto N, Lavin R, Berger B, Allegretti JR, Bry L, Gerber GK. Intrinsic instability of the dysbiotic microbiome revealed through dynamical systems inference at scale. bioRxiv 2021.12.14.469105; doi: https://doi.org/10.1101/2021.12.14.469105

November 2021: Gerber Lab Preprint

Dawkins JJ, Jessica RA, Gibson TE, McClure E, Delaney M, Bry L, Gerber GK. Gut metabolites predict Clostridioides difficile recurrence. medRxiv 2021.11.24.21266826; doi: https://doi.org/10.1101/2021.11.24.2126682

November 2021: Gerber Lab Podcast

The science behind recurring C. difficile infections


2021: Gibson Lab Awarded NIH Grants

August: Machine Learning and Control Principles for Computational Biology

May: Tracking the microbiome: purpose-built machine learning tools for tracking microbial strains over time

Sept 2020: Mahmood Lab paper

“Pathomic Fusion: An Integrated Framework for Fusing Histopathology and Genomic Features for Cancer Diagnosis and Prognosis” in IEEE Transactions on Medical Imaging.

Sept 2020: Mahmood Lab award

“Interpretable Deep Learning Algorithms for Pathology Imaging Analysis” MIRA/R35 NIH/NIGMS Outstanding Investigator Award

Sept 2020: Gerber Lab award

“MTM 2: The rules of microbiota colonization of the mammalian gut.” The Gerber lab in collaboration with the Wang lab at Columbia have received a $2.9M grant from the National Science Foundation to develop and apply novel computational and experimental methods to elucidate fundamental rules governing the formation and maintenance of complex microbial ecosystems in the mammalian gut.