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Ami S. Bhatt MD PhD, Stanford – “From precision microbiome genomics to precision medicine”

Hybrid - Wolf Conference Center and Zoom 3rd Floor, 60 Fenwood Road, Boston, MA, Massachusetts, United States

More than 1,000 species of bacteria, archaea, viruses and fungi live in the human gut. Far from being passive passengers, these organisms strongly interact with one another and with their host's metabolism and immune system. Compelling early experiments have demonstrated associations between the intestinal microbiome composition and obesity, cardiovascular diseases, and certain cancer chemotherapies' efficacy. […]

Richard Levenson, MD, UC Davis Health – “Novel Tissue Imaging for Faster Diagnostics, Better AI”

Hybrid - Wolf Conference Center and Zoom 3rd Floor, 60 Fenwood Road, Boston, MA, Massachusetts, United States

Light microscopy of tissue biopsies remains the central technique in diagnosis and management of cancers as well as other diseases. The brightfield (transmission) optical design of today’s clinical microscopes requires optically thin slices of tissue mounted onto glass slides, a labor- and time-intensive process. Moreover, tissue sectioning can partially or completely consume small specimens, leaving […]

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Harris H. Wang, PhD Columbia University-“Spatial metagenomics, culturomics, and engineering of human and environmental microbiomes”

Hybrid - Wolf Conference Center and Zoom 3rd Floor, 60 Fenwood Road, Boston, MA, Massachusetts, United States

BWH Computational Pathology Special Seminar Harris H. Wang, PhD Associate Professor of Systems Biology Interim Chair, Department of Systems Biology, Columbia University Microbes that colonize the gastrointestinal tract play important roles in host metabolism, immunity, and homeostasis. Microbes that live in soil are responsible for a variety of key decomposition and remediation activities in the […]

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Jakob Nikolas Kather MD, Msc – “Deep Learning-based biomarkers for precision oncology”

Hybrid - Wolf Conference Center and Zoom 3rd Floor, 60 Fenwood Road, Boston, MA, Massachusetts, United States

Precision oncology requires complex biomarkers which are often based on molecular and genetic tests of tumor tissue. For many of these tests, universal implementation in clinical practice is limited. However, for virtually every cancer patient, tissue slides stained with hematoxylin and eosin (H&E) are available. Deep Learning can extract biomarkers for better treatment decisions from […]

Anshul Kundaje, PhD – Stanford University – “Using deep learning models to debug regulatory genomics experiments and decode cis-regulatory syntax”

Zoom

Speaker: Anshul Kundaje, PhD Affiliation: Stanford University Position: Associate Professor, Genetics and Computer Science Anshul Kundaje is Associate Professor of Genetics and Computer Science at Stanford University. His primary research area is large-scale computational regulatory genomics. The Kundaje lab develops deep learning models of gene regulation and model interpretation methods to decipher non-coding DNA and […]