Building for Transformative Medicine, 60 Fenwood Road, Boston MA

Tal Korem PhD, Columbia – “Contamination and genomic variability in microbiome data”

Microbiome studies hold tremendous potential along with substantial computational challenges. I will present two computational approaches for microbiome data analysis. First, I will present SCRuB, a new method for in silico removal of contamination from microbiome data. We show that modeling the taxonomic composition of contamination sources, rather than trying to infer whether specific taxa […]

Efrat Muller, Tel Aviv University – “Methods for integrating metagenomics and metabolomics data”

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Speaker Name: Efrat Muller Affiliation: Prof. Elhanan Borenstein Lab, Tel Aviv University Position: Doctoral Candidate Hosted by: Jennifer Dawkins, Gerber Lab The human gut microbiome, and its metabolic activity in particular, have been implicated in a wide range of disease states, including metabolic disorders, inflammatory bowel diseases, and colorectal cancer. This growing appreciation for the […]

Vitalii Kleshchevnikov, PhD – Wellcome Sanger Institute – “Probabilistic models to resolve cell identity and tissue architecture”

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Speaker:  Vitalii Kleshchevnikov, PhD Affiliation:  Wellcome Sanger Institute Position:  Bioinformatician @ Bayraktar, Stegle, Teichmann group Host: Daniel MacDonald, Gibson Lab Abstract:  Cell identity drives cell-cell communication and tissue architecture and is in return regulated by cell-extrinsic cues. Cell identity is determined by the combination of intrinsic developmentally established transcription factor use (TF) and constitutive as […]